巴西专利BR112012011021A2 body cavity ablation device

专利PDF首页>>巴西专利

专利附录

专利说明

权利要求

类似技术

同族专利

引用文献

法律状态

优先权

专利摘要:
BODY CAVITY ABLATION DEVICE - The object of the invention is an ablation device that places electrodes on the perimeter of a cavity. In one embodiment, the alternating electric field is used to expose the cavity to sufficient energy for the ablation of the cavity. In one embodiment, two modes are used to expose different regions of the cavity to a different amount of energy so that the thermal effect is more uniform. In one embodiment, the electrodes have a relatively large surface area in order to prevent carbonization of the cavity, but are shaped to fit within a hole in the body. For example, the diameter of the sheath that houses the electrodes during penetration can be only 5.5mm.
公开号:BR112012011021A2
申请号:R112012011021-7
申请日:2010-11-10
公开日:2021-03-23
发明作者:Roger A. Stern；Jia H. Xiao；Jerome Jackson；Grant M. Glaze
申请人:Cardea Medsystems Inc；
IPC主号:

专利说明:

"BODY CAVITY ABLATION APPLIANCE" Descriptive Report The present invention relates to body cavity ablation devices and claims c) benefit of US patent application 61 / 259,973 filed on November 10, 2009, the content of which is incorporated here by reference.
the object discussed in the prior art should not be considered to be prior art b merely as a result of its mention in the prior art. Likewise, a problem mentioned in the prior art or associated with the prior art object should not be considered to be previously recognized in the prior art. The subject in the state of the art represents only different approaches, which in themselves can also be inventions.
The ablation of the inner organ of a body organ is a procedure that involves heating the lining of the organ to temperatures that destroy the cells of the lining and coagulate the blood flow to hemostasis. Said procedure can be performed as a treatment for one of many conditions, such as chronic hemorrhage of the endoInetríal layer of the uterus or abnormalities of the intact layer of the gallbladder. Existing methods for ablation include circulating a heated fluid inside the organ (either directly or inside a balloon) and laser treatment of the organ lining. The new # methods and devices may be desirable to effect «the ablation of the hollow cavity of the body.
Methods and devices are provided for ablating the hollow cavity of the body. The devices are adjustable to adjust the perimeter of a variety of organ sizes and fold into a small size for insertion into a small opening.
Any of the forms of modalities 10 above can be used alone or in conjunction with another in any combination. Inventions encompassed within this specification may also include modalities that are only partially mentioned or alluded to or are not mentioned or alluded to in this brief summary or summary.
15 In the following drawings, reference numbers are used to refer to similar elements. Although the figures below describe several examples of the invention, the invention is not limited to the examples described in the figures.
Figure 1 A shows an elevated front view of an embodiment of a body cavity ablation device connected to a controller system and a fluid removal device. Figure 1 B shows a screen photo 25 of a user interface screen of the controller system. Figure 1 c shows a picture of the r "3/16 screen.
from another user interface screen of the controller system. Figure 1 d shows a drawing of an electrode activation modality for a modality of a body cavity ablation device having 6 electrodes and two modes. Figure 2 shows a modality of a controller system for a body cavity ablation device.
10 Figures 3a-c show frontal elevation views of three or more modalities of body cavity ablation devices. Figure 3b is a partial cross-sectional view of an embodiment of a body cavity ablation device.
15 'Figure 4 shows an elevated front view of a modality of a body cavity ablation device using extraction spring or coil electrodes and pressure wires. Figure 5 shows an elevated front view 20 of an embodiment of a body cavity ablation device using telescopic electrodes.
Figure 6a shows an elevated front view of the interior of a handpiece embodiment.
Figure 6b shows a cross-sectional view 25 of an embodiment of the interior of the handpiece of figure 6a. Figure 6c shows an enlargement of
Part of figure 6b. Figure 7 shows a front view
S elevated from a modality on the outside of the handpiece in figure 6a, including length and width adjustments.
Figure 8a shows an embodiment of a fluid removal device.
Figure 8b shows another view of the fluid removal device.
Figure 9 shows a flow chart of a method of using a modality of a body cavity ablation device. Figure 10 shows a flow chart of a method of assembling the system components of an embodiment of a body cavity ablation apparatus. Figure 11 shows a flow chart of a method of assembling the system components of the body cavity ablation device.
Figure 12 shows an elevated front view 20 of a method of testing a body cavity ablation aftertreatment apparatus.
Figure 13 shows an elevated front view of a method of testing a body cavity ablation aftertreatment apparatus.
25 Figures 14 and 15 show side elevations of the ablation test material- Figures 16 and 17 show tables 2 "
- g l 5/16 and 2b, which show the results of the ablation tests. u Although various modalities of the invention b may have been motivated by several deficiencies with the state of the art, which can be discussed or alluded to in one or more places in the specification, the modalities of the invention do not necessarily mention any of these deficiencies. In other words, the different modalities of the invention can correct the different deficiencies that can be discussed in the specification.
10 Some modalities can only partially address some deficiencies or just a deficiency that can be discussed in the specification, and some modalities cannot address any of these deficiencies.
In general, at the beginning of the discussion of 15 each of the figures 1 A-8 is a brief description of each element, which may have no more than the name of each of the elements in one of the figures 1 A-8 being discussed. After the brief description of each element, each element is discussed in numerical order. In general, each of figures 1-17 is discussed in numerical order, and the elements within figures 1-17 are also usually discussed in numerical order to facilitate easy location of the discussion of a particular element.
However, there is no place where 25 all the information for any element in figures 1A-17 is necessarily located. Exclusive information about any particular element or any other aspect of any of Figures 1A-17 can be found or contained by any part of the specification.
In various places when discussing the 5 drawings, a series of letters, such as "a-z" are used to refer to individual elements from various series of elements that are the same. In each of these series, the final letters are integer variables that can be any number. Unless otherwise indicated, 10 the number of elements in each of these series is not related to the number of elements in other of these series. Specifically, although a letter (for example, "a") comes at the beginning of the alphabet than another letter (for example, "e"), the order of these letters in the alphabet does not mean that the previous letter represents a smaller number. q value of the previous letter is not related to the posterior letter, and can represent a value that is greater than, equal to or less than the posterior letter.
Figure 1 shows a top view 20 of an embodiment of a body cavity ablation apparatus used in body cavity organ ablation methods. The ablation apparatus 100 may include a manual implement 101, a power supply 102, a controller system (a controller) 104 and a suction device 103. The manual implement 101 may include a head 110, a reservoir 113, a connector 150 , a suction port 140, a sheath 130, a tube
- suction 133, one or more insulators 120, 121, and 122, one or more electrodes 160a-z, one year piece 180, a length adjustment 182, a width adjustment 184 for implantation of the device. The ablation apparatus 100 5 may also include foot control 186. In other embodiments c) ablation apparatus 100 and / or manual implement 101 may not have all the elements or aspects listed and / or may have other elements or aspects instead of or in addition to those listed.
10 In this application, the term "perimeter" when used in reference to the uterus refers to the exterior of the ablation or endometrium region. The ablation apparatus 100 is an example of a system that can be used for the ablation of the inner lining of a body organ that can be hollow. The ablation apparatus 100 may include electrodes that can be arranged in a pattern that makes contact with the surface area of the cavity of the hollow body organ in close proximity to the perimeter. Energizing the electrodes can result in a partial or complete ablation of the lining of the body cavity without the need to move the electrodes, although the electrodes only make contact with the surface area of the organ in the vicinity of the perimeter. The user of the ablation device 100 can be anyone using the ablation device 100 during a hollow body ablation procedure. Users can understand doctors, surgeons, nurses, veterinarians and any support staff who may be helping with a procedure, for example. The procedure can be done in an operating room or as an outpatient procedure, for example.
The manual implement 101 can be used for the ablation of a hollow cavity with anterior and posterior surfaces, while the anterior and posterior surfaces are separated or contacting each other. the manual insert 101 can include a head 110, which can be of any shape, according to the cavity that is to be etched, and / or can be adjusted to approximate the perimeter of a body cavity organ. The manual implement 101 may have electrodes arranged in a pattern that allow placement on the perimeter of the body cavity organ. The manual implement 101 has controls (for example, on the manual implement 101) that allow the user to reduce the overall profile and size of the manual implement 101 to allow minimally invasive access, to be able to better conform the organs with distorted cavity shapes. The manual implement 101 has the advantage that the manual implement 101 is able to collapse on itself to form a small tube that fits into a small diameter opening. In some embodiments, the opening has a diameter between about 4 and about 7 mm, including but not limited to
4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, 5.0, 5.1,
5.2, 5.3, 5.4, 5.5, 5.6, 5.7, 5.8, 5.9, 6.0, 6.1, 6.2,
6.3, 6.4, 6.5, 6.6, 6.7, 6.8, and 6.9 mm. In the case where the diameter is between 4 and 7 mm, the manual implement 101 may collapse on itself until the manual implement 101 has a diameter of between about 4 or 5.5 and about] mm, including but not limited to The
4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, 5.0, 5.1,
5.2, 5.3, 5.4, 5.5, 5.6, 5.7, 5.8, 5.9, 6.0, 6.1, 6.2,
6.3, 6.4, 6.5, 6.6, 6.7, 6.8, and 6.9 mm. In some embodiments, the opening diameter is about
5.5 mm, and the diameter of the manual implement 101 when collapsed is less than 5.5 mm, which is less than the diameter of the heads of the ablation devices of the prior art. The manual implement 101 in the invention can have various geometric adjustments applied through operational controls of the handpiece 180 of the manual implement 101 that alters the size and / or shape of the head.
Power supply 102 may include a transformer for converting voltage and / or an alternating current source, such as a variable oscillator, which may generate Alternating Current (AC) Radio Frequency (RF). Alternatively, the power supply 102 may include a generator. The power supply 102 controls the frequency of the alternating current that is output by the power source 102. The suction device 103 includes a suction tube 133 and a reservoir 113 and can act L
J 10/16 "to remove excess fluid, (ie liquid, vapor and gases), from the body cavity organ, before, during * and / or after the ablation process (eg the procedure) (no is required to remove all fluids from the cavity.) The suction device 103 can use any fluid removal method, including a pump, suction, and / or aspirator to remove fluids.
Controller 104 may include an algorithm that allows control of alternating current 10 (AC). Power supply 102 may be a part of controller 104 or separate from controller 104. Controller 104 may be able to apply different patterns of alternating the polarities of the different electrodes of the ablation device 100, changing the 15 polarities of the electrodes in various combinations to perform bipolar ablation between the selected electrodes or monopolar ablation to a neutral electrode. The frequency, voltage, and / or current can be adjusted to adjust the dimensions of the cavity to limit ablation effects 20 for the desired tissue or layers of tissue, and to minimize side effects, and can be used to determine the total doses of therapeutic energy, and / or determine other configurations, such as energy, duration (the amount of time) of application of the electric field, 25 etc., as shown in figure ID for a coupled pair diagram of bipolar electrodes and figures 16 and 17 for the energy conduction algorithms that can be
¥ â
J d 11/16 "used. The power supply 102 in controller 104 is capable of conducting multiple electrodes in several bipolar pairs located in the 5 manual implement 101 and in the vicinity of the perimeter of the hollow organ, in order to automatically sequence through a set desired bipolar or non-polar ablation polarities and / or algorithms Controller 104 is discussed in more detail together with reference to Figure 2. In some embodiments, the head 110 is generally a triangular annual implement 101 having an approximately isosceles triangular shape. The area distal to handpiece 180 is the base, however, even when head 110 is a parallelogram, the base can still be thought of as the distal side for handpiece 180. If head 110 has a shape more circular or oval, the base can be thought of as the area most distal to the handpiece 180. After the total opening of the head 110, the base 20 can be between about 2 and about 4.5 cm and the length after s the complete opening of the head 110 between about 4 and about 6.5 cm. Other modalities of this device can have the base of the width and length generally more or less, depending on the size of the organ 25 to be etched. The term generally triangular means that the manual implement 101 can be of any shape, such as a generally triangular shape
"" q L) '
T 12/16 "(including a rounded triangle), a square, a parallelogram, a circle, ellipse, rhombus, spiral, etc. m, but in the case of a square, parallelogram, circle or ellipse, the" base "is the most distal part of the handpiece and the 5 "sides" are the parts on both sides of the "base". The shape may depend, in part, on how far apart the sides are in the sheath 130 and / or the handpiece 180. In some embodiments , the base is the most distal side of the manual implement 101 and after the complete opening of the manual implement 10 101, the base can be between about 1.5 or 2 and about 5 cm, including but not limited to 2.1, 2.2,
2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3,
3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 4.0, 4.1, 4.2, 4.3, 4.4,
4.5, 4.6, 4.7, 4.8, and 4.9 cm. In some embodiments, the 15 sides of the device are between about 3.5 and about 7 cm, including, but not limited to, 3.6, 3.7, 3.8, 3.9,
4.0, 4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, 5.0,
5.1, 5.2, 5.3, 5.4, 5.5, 5.6, 5.7, 5.8, 5.9, 6.0, 6.1,
6.2, 6.3, 6.4, 6.5, 6.6, 6.7, 6.8, and 6.9 cm.
The reservoir 113 can be a part of the suction device 103, and can be any type of reservoir that can contain body fluids (i.e., liquids, vapors or gases) without spreading biological risks. In some embodiments, the pump 214 in figure 25 2, can be any pump. In some embodiments, the pump is a mechanical pump, a finger pump, a syringe pump, vacuum canister, turbine pump, peristaltic q pump or another method for creating negative pressure. Alternatively, the system can be connected to the vacuum wall that exists in the hospital or operating room.
5 In the modality shown in figure 1A, there are several insulators 120, 121 and 122 that work to keep electrodes 160a-z working. The electrode shells can be continuous, or scratched on one or more sides or in a generally spiral pattern to facilitate flexion and adaptation to the organ's perimeter. The side insulating walls 120, 121 and 122 can be continuous, or scratched on one or more sides or in a generally spiral pattern to facilitate flexion and adaptation and to the perimeter of the organ. The cross sections of the electrode can be of any geometry, including circular, elliptical, rectangular, or non-symmetrical 'D' shape which may be preferable to maximize the electrode surface area to contact the organ wall for a device that must be introduced through a small diameter opening. Likewise, the cross sections of the side insulators 120, 121, and 122 in figure 1A can be of any geometry, including circular, elliptical, rectangular, or non-symmetrical in the shape of a 'D'. The cross sections of the insulator can correspond to those of the electrodes so that, for example, the cross sections of the electrode are 'D' shaped and scratched, the insulators 120, 121 and
) $ 14/16% 122 are D-shaped and work to separate the D-tube electrodes 161 from the D-tube electrodes 162. The »side insulators 120, 121, and 122 can also be hollow to allow the pressure and / or signaling wires and conduits 5 or tubes to be inserted. Side insulators 120, 121, and 122 can be constructed of Polyether Ether Acetone (PEEK), or any other non-conductive insulating material. The melting temperature of the side insulators 120, 121, and 122 must be sufficiently high so as not to melt during ablation (for example, it may be desirable for the insulator's melting temperature to be above 400 degrees Fahrenheit).
In the embodiment shown in figure 1A, there are angular insulators l21a-z, which can be 15 rigid D-shaped insulators and work to separate the D-tube electrodes 162 from the coil electrodes 163.
Angular insulators 121a-z can be constructed of polyimide or any other non-conductive insulator.
20 In the embodiment shown in figure IA, there is a distal insulator 122 that can be constructed from a strip of non-conductive material. Distal insulators 122 work to separate coil electrodes 163 and give electrodes 163 unique flat flexibility. The distal insulator 122 can also be highly flexible to bend to allow the two base electrodes 163 to bend when the head 110 is retracted and inserted into the il r} µ 15/16.
m + sheath 130.
The manual implement 101 can have
W various geometric adjustments applied through operational controls on the handpiece 180 of the hand implement 101.
5 Operational controls may allow you to adjust electrodes 160a-z to adjust the perimeter of organs of various sizes and shapes. For a triangular-shaped cavity organ, such as the female human uterus, the settings can be configured to allow adjustment 10 regardless of the base and length of the triangle. For an elliptical shape, the adjustments can be of larger and smaller elliptical dimensions. For cavities of other shapes, suitable dimensional adjustments can be implemented. Adjustments to adjust the dimensions of the cavity can be used to determine the total dose of therapeutic energy in joules, or other adjustments, such as energy, time, etc. The sheath 130 can be attached to the handpiece 180 and works to protect the electrodes 160a-z 20 while the handpiece 101 is being inserted into an opening of a body cavity organ (when the device is retracted). The sheath 130 can protect at least the side electrodes (161, 162) or all electrodes 160a-z during the insertion of the device 25 through the opening of the organ. The sheath 130 can be constructed to have an atraumatic tip. When retracted, head 110 can slide into sheath 130. Alternatively, the user can slide head 110 out of sheath 130 when desired during a procedure. Sheath 130 can be attached to a rigid coupling for length adjustment 182 (for example, button or fixed device), so that by moving the length adjustment the sheath moves in the same direction by the same amount as the adjustment movement the length.
Each modality described herein can be used or combined in any other way with any other disclosed modalities. Any element of any modality can be used in any modality. Although the invention has been described with reference to specific modalities, it will be understood by those skilled in the art that various changes can be made and equivalents can be replaced by elements of the same without departing from the true spirit and scope of the invention. In addition, modifications can be made without departing from the essential teachings of the invention.

权利要求:
Claims (4)
[1]
1. "CAVITY ABLATION APPLIANCE m
BODY H ", characterized by comprising: - a head having at least three 5 electrodes, at least one insulator and a sheath, said head comprising an elongated member having sides and a base, said sides and base being flexible; - a sheath; - a head connected handpiece 10 comprising width and length adjustments that can adjust the width and length of the sides and base of the head, wherein said head can be retracted into said sheath using the width and / or length adjustments.
[2]
2. "CORPORAL CAVITY ABLATION APPLIANCE 15", as claimed in 1, characterized in that the sides and the base are flexible due to the use of flexible electrodes.
[3]
3. "BODY CAVITY ABLATION APPLIANCE", as claimed in 1, characterized by qs 20 sides and the base being flexible due to the use of flexible insulators ".
[4]
4. "BODY CAVITY ABLATION EQUIPMENT", as claimed in 1, characterized in that at least one of the electrodes is a coil electrode.
25 5. "BODY CAVITY ABLATION DEVICE", as claimed in 1, characterized in that at least one of the electrodes is a tube electrode, the tube
"having a cross-sectional shape that is non-circular..
6. "CAVITY ABLATION APPLIANCE
CORPORAL W ", as claimed in 1, characterized in that at least one of the electrodes is a scratched D-tube electrode 5.
7. "BODY CAVITY ABLATION EQUIPMENT", as claimed in 1, characterized in that at least one of the electrodes is a metal chain electrode.
10 8. "BODY CAVITY ABLATION APPLIANCE", as claimed in 1, characterized in that at least one of the electrodes is a concertina electrode.
9. "BODY CAVITY ABLATION APPLIANCE", as claimed in 1, characterized in that at least one of the electrodes is a braided metal wire electrode.
10. "BODY CAVITY ABLATION EQUIPMENT", as claimed in 1, characterized in that at least one of the electrodes is a telescopic electrode.
20 11. "BODY CAVITY ABLATION APPLIANCE", as claimed in 1, characterized in that at least one of the insulators is a flexible insulator.
12. "BODY CAVITY ABLATION APPLIANCE" ', as claimed in 1, characterized in that the diameter of the sheath is between about 4 and 6.5 mm.
13. "BODY CAVITY ABLATION APPLIANCE", characterized by comprising:
% - at least one type D electrode, said D-tube comprising a tubular electrode having a
W forms in D, so that the innermost semicircular region is removed to form a tubular electrode with a cross section "D".
14. "BODY CAVITY ABLATION APPLIANCE", characterized by comprising: - a head with a triangular shape with at least three electrodes, at least three electrodes 10 in the perimeter of the triangular shape, at least one of the electrodes is a preloaded spring , which tends to push the head in a triangular shape, and no electrodes are located inside an inner end of the perimeter formed by at least three electrodes.
15 15. "BODY CAVITY ABLATION APPLIANCE", characterized by comprising: - a head having a distal end and two sides, comprising at least six electrodes, in which two electrodes are located at the distal end, and four electrodes are located at two sides, and - a handpiece, in which each of said electrodes can be activated separately.
16. "CAVITY ABLATION APPLIANCE.
BODY 25 ", as claimed in 15, characterized in that the distal electrodes at the distal end and the two sides can be activated separately from the proximal r t 4/4 electrodes.
17. "BODY CAVITY ABLATION APPLIANCE" ', as claimed in 15, characterized in that the activation involves the application of an AC or RF power supply mode 5.
18. "METHOD FOR ABLATION OF A BODY CAVITY ORGAN", characterized by comprising: (a) providing an ablation device including a head having at least one electrode, at least one insulator and a sheath, said head comprising 10 an elongated member having sides and a base; a handpiece connected to the head comprising adjustments to the width and length of the sides and base of the head, wherein said head can be retracted into said sheath 15 using the width and / or length adjustment; q (b) position the head in contact with the tissue at the perimeter of the body cavity organ; (C) providing RF energy through the electrodes to the tissue, where RF energy is sent 20 by applying a first amount of energy to a first part of the body cavity organ and applying a second amount of energy that is less than the first amount of energy to a second part of the body cavity organ.
d: r
P 1/23 «100 122
V.
',, 0) Í ,, 6)'), 60
4.
101 A '. ))) l · 130. 180 -.
182 IT'S 184
P | 1 f t ',,,),)) 186 186 104 FlG. 1A
W "t u. & · 'Rr" y + · F ~ k "
S 4, .. '. "' Y": "·" '' $ ":. * ¥)) Í *
t r 3/23
F 0
&
V "e6 K 'C: · m
Ú is t "'O"' ~ 9 "4" <%) "." U | 7 "l) E) ~ ~" = M lI '| Z> + ~ ~
U <C
H =
O 4 - ».Ê 2) · ·· '-O g'" l 'Z M.
'g
AND A | ) l ·, -) ~ F) I - - "
'El t
The "g l" "''>" l 'and "T W.
k-
A Ü) '.I. "-". "· .-.,' '+'" O ~ Z! L O Ll- .á ¥ "7 .l ^: ts. _ * G) j'i" " -. :: "'" 4 "m. <'- E "·' ::. C>" = & á = à =: n '"" S3 ~ ~ 7' Z «,. · -:. "....
_ i. - ': + BL:'): P -. ',' T !; "" y., "- '" · - "! °' jCj -" <^ 6
D it # F t 5/23 Lead to Wall 200 ru, rOuttet 228 Relay 224> 3) ct2 :, G!:, :, :: ° 'Am, ::' "'')) Í)) "" "° '" "' Relay 226 6) Output System)") l) input System: 292 '! I)) 204) '..
'"^ Memory System X Processor)! Pump 214 Lookup Table of I - l System 2QS Í Power and Duration of Time 216 FlG. 2 i
¢ ¶ ¥ '6/23 302 P 30OA.-)') ,,))) 3'0) '. Fâg. 3A 31.2 314 316 320 318 320 Í tf "r« 'í ~) L' .W ,,, j)))) '))))))) /') ")") ',) ) '"" "=)) U)))') ', - ,,,'" "'íj ' ~ _A28 326")
ÀJ '¥, § 324 y: "" "'
J 330 FIG. 3B FlG. 3C. .. ..
480 t 437 J 400 436 462/420 / ^ 410.
.
K
È 421 170 m, 438 FIG. 4:
+ - - 500 580) ') "° -i -ji / already ° 564 -) ..
l530) FlG. 5
+
O
))
3 "" '' 'jE r "". t:, € 0 t "Z '
K f, i. . . 'M)! = - ^ ''. · "'I ..! R í a!' '" -' l «
And j; ÊM I "F,, $ C L- j: faith P · Y - .. 'i- pb, k: | ..;. 4- í.i.,: CD >' '!":' l) kj, í "j: · 'Ç'" I, 'f :, I'. 'ç'.j -S,: à' : l '% - "' @tl 't' 'Fg, : '-' 1 '' - "f '" sà ·' - 'K l' CD C g: '"' 5":, 'j í. "Ay ' · Tq" "" "' =' - · · U- '. : l i. Z-! "E" Ç '·': "%" is "" '"!'" E ": j $ e '" "! - Z' |:% -> íy S" '- i "'" '"" " ":)) '1'! J]" i 'j, i, Ê "))')) ,, · .4p" '"" OC;: &., R «"! 's "1., h j" 7y. . ". '" ".T"'.
! g ':;.' "! '-, ·" l' "'à: rii :., S, ·' tí" "t- f: i,,, ii ': i l,', '9b: j'í"')! 't yi Ú: íí ":'" "" "" - '' # '. -,' Á ©
CJ · i . $ There
CD d | "" ,, '":%!" <, "" "" ·' ':; I "" 1' - "": {'"¢'" q: 'l í' í "€" i , m "'r'" p "'" ggr' | '' g ""! '"í« l | ":. 5"!' "E '" "í': ' '- 1 "í: i"' 'm'.)) B)) '.;) t) jTj),')) '::' "" 'E) l'í),)) d íí "i Z: && - j '·' '">" L' "V" " · '€ 4 · Ê' l" '"j íii:' j |! D": È ": J-" ' : "" lii! ') I), zÍ! Í i2)) l |)' "))) ..! ') l # ± ¥ j. · À.w.
lkE% '% - t, - · "' · i ·" i 2 Ê '' í A '"Í. £ ,,:, j o Z' j: '' éwj í.; '.' W - 'áp' nT, ': ü ' - · - I 't' "G" "'-' · j '.Yf. í-'i · t E Ê '), + t. & -: .... Á ¢ · E "'.' ', # = .— 2 l i <¥' ·" t 'k:' · · · .'f. tç. "..: -.,.« £ J b ç 'r.' G '· Il k' * '= i l.,' 'r r "12/23 a
W i. :, l '1 ·: l'
S * I '") jÍ'im ¥, Xm% b. - à.' '' '"' 1 , "/ ,,): o" "4 / Àn '/ / UÍ ij /:;! 1 7Jjr O, À, ',; S:' -}, µ. "'*' P9- '"':.. "" U \ "'' and 0 r ·" -. Jr ': - " , ° \ T - "t"; "" mf>; / '"" i' "" ". & 4 - ,:, .l.:. U ', E. *' a"% '' · " , ·. ' "" Kl <"" '"wS, NJ: í ^ ;; -:": i': "; A.j €. r; · '":' ·" .t ·. & · P e '') :) SJ 'f, T: J "' ÍÁ,: '" "") ° 0 /. , Ê & & jj "; ç - '(' m" "" "te IF =! 4-R ''" · "· -H ku: <; à: s" mdq '· ..K f A,. l. ". is" ~ "'¥' = -— ^ =: '.4È;' -, &" 'r. T jl ik6i' "" a: i "· .'í r,." r. 1 · E "'" "" "" -, / T-.,. GE ,, j,' "j ,, , t ',, U" CA ;,' fjp-, ), lyLj ; " ug jj '"/ J" -i "'", '".,> Z ,, · ¥" (I - ..
Secondary filter 830
Fluid Separator l à99, 825
- Á ':' ": 'i} i ¢ 0j: · it),: i) m e-"' ump 8á2 i), 3iitigiilii! Iliii |
810
+
" " 4'ê * '['! '|' ' q ... * -. AND . . . .— K FF
:: l: i'iÊ '· ii;:' i z; | ".-. b% b-., .. '%
Activated 824 Carbon Filter 820. "· FlG. 8A í,
. -
W Cardea Aspiraiton Bottle "~ e ¥ m a -." + T-. ±>% '- *. t y Z ".fy · - .. Tf 6> ..
f "".
.. '";:"' °, .. - ~. , -— acuum. . "L + .-" "" g ". ' .3í.tj ' -. Pum "-. 'K à' "4 ':!' 42 'A' ·" "'": W 4 .. ..- "*" "" ·' '* ". "*" '* <· M "' t -, 'cu-. F'. Í, N" '' »n <g ·. "4 'Z ¥" ":! .. 4'. €.,. 4 - I ... k 'í t K.« T' · ". R% "'o Patient t" · ctivated. ,, - à "7 ontact Carbon = 4 '"' & 3 "·" *, t + ·, w. G ,, * '' - .. "F". "6. '" F «P t ·. , '' q, ". '6 .t. t., ¥: ^ A'G'A:' t ^ p; 'L r« d, <¥. "Er", "" "¥"' "y '' L '"" · .t ¥. r,:. m · · t 2: "g" 'q.:' x-r .'4 ", ·· " · "" j "" "¥ -" ... · "" K q.
L t 'Kkc "' p- ^ '. & - t' 'á L!', ¥ '-X;.":; -. . . . , è "'ikí' · H
7.. S. ."
S .L ti-; = "'í,'." "". ·: * '¶':. àd ',: Fr' "r. ik Z $» "i" "" · "iZ} # -! "$ + · 7% @ i: F. t ':. · I Y" ~. k "4 '..
. . b L "econdary ·. í. -". ,. - ' · P ' .
¢ "m. 'Ilter *' P + '). R 7" j' 4 ¶ f i .d w j "% t F! G.8'B l 'L {'. -J
Start
I lnsert ablation device into. Gollow body organ QZ A
| Adjust device to fit perimeter I of hollow body organ 904 ~ WII
Purn on RF controiter system 9'06 l j
Choose power and time for private organ or size 908 wmv me
I lmplement'Mode 1 910 I lmplement'Mode 2 412
And "na)
,
"FlG. 9
| 7 1 ¶ 16/23 e.
V, 1000 Start l Assemble ablation device 1005 j Attach tiquid removal - I device to ablation device 1010 | 't, Attach RF controller', system to ablation! ' device 1020
And End -) FlG. 10 k 3 17 [23 to 1100 »Start I Assemble handpiece 1105 I Assemble sheath 1110 j Assemble electrode apparatus 1120 li Connect electrode I apparatus and sheath | mo handRiece 1140_J End FlG. 11
È k) 18/23 6 «.
Y »è, 4: +" r "r '" ' <'' "'' Í" 4 "" 'Y d' · -, i "'7 .® -. .. m,. . : -a * p - t &. -. · E L. "l _ '" T "l' · 'ej! J: Z' -4. -;. '' ''" "·" È ae ¶ .. *., 0 Pij '' "" ' + "4. - '$" "- -" -. · Í ""' "'c pf t ·,' à" I ll "':" "i" - -' '' "+ - * 'z % I,, * yk% H e-4 í ""} '' "'A:'% -" <% .. ". w. .
-. U 31 i Í "'" g. - · ". '"' "Ã zk | = |.. M
4. 4 "- fú". ' 1 · "E T] l" ~ '· "í" 4 "' F b .. d..
t & j) j - * · "" '·' í ,: b- '"., k'" Y '".'," ÇJ S,, "" y "'',. F w k., p '"i7 I & K D,'" · -. · - d '', "· 'ii í. % '". Ab" ".' '"f Nâ:. g 'l' È "" '",." N t »» "m ¥ -" g; .The. y- -Z'l4k. ·. '"' ".
. . . .. -: t) | ' - -'Z "íf '" "·" "-' '[-' ·. 4" "." + | t jjL n '. . - Ê ,, '- Í "j'" '' '% w
Ú · à, b 'G. . 'B
Z, 4 'f. . k - m · .F ': "p - ¥' F '' F .. l '' 3l. - Át" - "" '"" "*' |, Inl; r,!;"} "! '| et} 1 ': | 7] "):"! n "l: yYT IÍ]
È tri o l "j jg 'sÁÁ ~ 7H'rçNi.')! L $ F <tZl'bí
X ~ = 4> E e "'d 2 3 ~ À 1 ~ á ~ cn qj O F"' =, C J T ~ e. i Kll g, 19j23 and
V!
S, â '! m)) ") 'P í) 2, ÊÍ" "' '+ â' Á) t '.. = -':) Z) Z)" '- "· t" = · E9.' -. "" O CJ · "k" X ¥ C · .L.-Á -. X '' "" "" - '. ., G-m, ã7 G .m-, «, £" xu "-" <'-, "1 <" ·. "'" ""; '- ". ~ 'Ê.,, N3i "" "Rí'" Í "4'Y" SÍ :, t ·: ': À "-, ;;'" "" '"" "'. · :: ', µ: ; .4.. ± · T. 'J, S': S, ^. "And . "'-' ú 'fl!' i; '4": Ê-2' - ": y: |" t "yg -M'k" - ": t" ['· .i- · |; z " - '' "i E. «&. ~ L": j'Á: tii "" ": '" 7j @ l ".;' Iá ']!' T ']") ", j'j'Lj :: 4" ") "
D
È Ê 'n "t = C' t m ~ ~ En U3
O É- "° Q.q Ô
L) '
_ "v r · 1 'P' 'tè!' - - · 'l.
W ';. · B f - ... ã t i r. . ' çq ¢ i '.' ..: 'CJ µ. ..; í ¥; . . J ':'. , k :. , k4 ¢, ji <'"., · · g' $" & 4, 'x'. r! . "'" b.4F'wmÀ. ¢ - ": f.t." + r · · xja ·> 4- & L "ií"' "" k.jj, -3 ':' tF :: t. Tj .. "¶¶% '., E ,,, à:.,. .. t'." '"Jít {· .i.. À:;' á ,.. - '"' .E '
T "t '-" i, M-X: «' m b .w! ' + 1 (b ··. <": &, U '" "· je á' '-' #.
! "))., :) T ', Y:, Hi {) |)',)) íÁi-. J," -.'- ZÁ "ZY 'n 4". , ... ..
y. "a -. * 'k" ": d" "' '"' "'" "" "" and "" ".W · ç:'" '' "·" "L '+'. * ':' L8i, ~ qO))" '·' "" '"A'" '"í' ·· - · b. SL l., 'P') tjí 'T · j qjfQ QÍ' · '"%' - -.- ¥ ¶ '· y. - 'M'. 3 r. -. oô |, â | "I '" "" -' "" "., .. ¢" 'K "," "' '' ..
'f µ rj: ó:' 8 "" .í "" * '' {. "'7s, u' ··": '; '-' í.> ") '%" ç': 'm IEJ! ·· "r -% · # '"! I '' '"- · ú Í; jq ·.'". ¢ E ÍÍ "l" ': j "" "l,': ''" | i —— rz j "í 'à) m
M jaj 'I
È l {'' * '' A'- "! '" T B ""' '. '$ "" "' '". '".g'S';, · q ° d- '4 | ií: T,: 2.: d :, e;: K =« !:' k "% | : -à. :: -; z ': 4' : "^ ^^» ^ A i. µ m '"" "U.
- and
O | ss] ': "¢': ¶k-7) a" r ", -í '" A'4' '"' 'j' · t, §> '"' "- '' t ', jj ), "'tiuu $ !:. "í. ' :. " The ·,.. . k. '"td t." b, "Y' · t .. .-. 4" K. . Z 0 4 '' ": '" ·. -p · * '"" Y "' È 'and ... .i' '" "....
p t '' l | ffqlffT 'jíj "1'" "'"' "'P <¥ -: .t' I, Z íl 't'. r, 4 'k, <d · ·' j t. 4: · 4 "&.
'·. r, E to "F.
The T: '- ·. í4r 3X k sm 3HLLN3nç + g., "~ W" "yX - ··
AND
O crj € w 'Q = UJ E fZ O
U j
L 21/23 and
H b Êl i P lj. [4 &. .
· W "" · . . . ¥ · í -m P ¥ r. · '")'). '4', !!) '|). -G! ~ R. D.
: '".. b .. ,, y". . 0 ·. · - ^. 4 t and · T '". F" 4 · +' '' '+ l'f. · ¥ r '· ¥ f t $. X F i · · e · · íp $ "-í '· *. ¢ F to 3r +,'. *. K% Y · r"
Q + - t. % ".. K · · · '' · · 'è -. ¥ 7 L!' 'Laughs Lj.'). S ·,. 3 * á ¢ *
4. T $ r 4. > '·. - í. d
6. ·· t - «k '.
· 'X.
b- · r k "L ·" · í · YL 'l' · '"' m · '+." - ".. ¶. a" 7 4, | " ,, ':' ta" + ~ · · F · # · .. · P O Y «- a jF · q t —Ç" - U + "· · -. J r. . m " '" ¥ T ", =: - * K." .
, ' - B.
»· Yr - * ~ e a- q · b W ç" ¥ + 2 n t
L ·
4 .., "r ¢. And" "'"! "'" Μ, ', ")'" ': W k 4 a ^ *
Y '¥ · ·% e · § í j · · "t · -." .e. ^ yík t-
L "'· S ·. M.> P:, i! Ií.% E q. · R * € 1 , Z k.. € Ç a.
.,. . . ¥ - ", please". . 'r ..,. . . ,.) ·,, ·. :
E · bf "LC) -,., -: i. I: + e; r. Is · *" r. '*) "'", jj! g_j! j)))) -): 1st. : Fç · + ·· + i + e h '* à ¥ t E' Ç tt '")! |,)'" L) 6 ';) ") f!" I'í |; í'!}: jj! ')' bí "))))))! 1) T}! |," 'í, t' {,) ,, ') ,,' È) ,,, T,) to 'íj :: : "ok - · - S-
Z and € ·· a. · F: .q ': t «. y .Á4 '"¥ ·. * ài §.' F y e i r. [
B N Hey 'Ü:' "" € i'jt,: «» K 'j! + & € · t .S: '% $ N P, t /! í 4 K ·> '"'" at -4P -, 4 and "':. h àF': l. b.; and # 'L; -' a" 4 * "" Í ": '!' 1 $ * A '' · {· "« ":" 't1 .í "- l' '· V" i} -Fg' | ' i) t, ',;:' | t ', ij) i, "t ¥:" q "':" "i · 'c ·" -.:'t!i ","; ü: "í' i 'i' ', L' í - 't (! jt' - +. ·% T '7 "',, 'i' {'kt" i (i $ i "E p {.j J : ) k ',! q. jl,'! mt-j 'T' · L! ·.: "" "'· jí." "· l'.
K 22/23
E e èa ¢ D ~~ ld <D <D ~ <D ¢ © ~~~ | ~~~ o ~ | ~ womwm ©
C aQ) ct) '
Q O en
O ~ t
F ~ © ¢ D (D N -> - m ~ ~ <D © oH © ÍmK © © m ¢ cDLD <D © u> ©: r f N 't
The R -7
E "q ívj lc> cd m Kn u7 q ¢ d © ld uj Lê) gn it> µ uj 47 © ujjuj tn in rn ld ld cn
Q m
O
UJ 0 OOOO OOOO ooDooolooooo | = Dooooo E n ¢ n ^ n nrnmm mmnnmm [mmn © nImmnnmmm çq Qj m £ F rLnLn © D qoo ooe0molo ooomLDu> Kjo inLDKo ocr> c '> m C4 C4DIY ¢ 4 uju7 ¢ 4 uju7 ¢ omKDu> © w ~ IC> U)
O O 09 a. ¢, m .C 1 çn E "d oooo q ooo nw« n ~ «. Ooooookooocjkmao" ooo, E a> aj0gj o) Q) m0 t tm m ftRa) 00a) 0ÚD <D (o © a> q> q ) | i0mQmm0 = m = "°°" "° Iwmm ©________________ l" "" "°" ° ~ w ~ w +> -> - ~ lm © m ©________________ Fm © mm ©________________ ©
O (D Q-: E)) z2z2r "- | 333: 33 | 33333 | 3333g33 ã 2 © u7 © mto4n ¢ u4uj0U> Lr ^ D LD | lntDu> tnm .c ¢ 4c4é4c4 cv« cv «· · - ' '"r cYcyc4eYfcq c4c4 ¢ Ycycq c4 uãIAônadõaa¶ <Y¶¶", ^ nnnnI # C! à) m [¶m4 ro <onm c4m¶u> çDHlmQjoNm¶Ln <D ~ ma> o E <~ tf m H mmm <N 6Q) = mmm "Um" DH> mpmppp "omUp" smmmm "om
OOOOOOOOOOQOOOOOOOOOOOOOO
OOOOOOOOOOQOOOOOOOOOOOOOO 0OO00O © OOO © 0O © O0O00OOO00O 0 ¢ 0 = O OO 0O = QO ¢ OOO0 ¢ OOO ¢ OOO «jc" jcj ¢ 'j «jcjcj cq ^ c'jejcmyj cqcn ¢' jej cj ejcne OOOO 0 4q «jujuj mtnto« jc'jc'j c4nc4c4 LnLcjínujuj <D üjujúj © f- mLDtn ~~ uj ¢ r oao OOOO oo0mõo OOOO Q OOOOODO ajo) ajmajajaj =! Sy = ! 0CD) oQj © CDCD t ujtejuj oodo oaoooo Ujtsjujuj UJ OOOOODD ~~~~ w ~~ S! mm © m © © © mm © mm ttjujuj uju> Ujtnu> u) Uj © úju> LcjLoLouj ¢ © U) ©% GG " "" "dóóOôóOóóá ccicÔcDÕÔcó <ÔcÓ ujujuj u> u> touj ujujtoujujuj u> u>« juj uj NCNN C4C4C4C4..... © ~ m © Sy ¢ n <Ln <D ~ © ojD T— mmmtrt C'4
'| : 1/1 b Juice k y "body cavity ABLATION device", - the object of the
Y invention is an ablation device that places electrodes on the perimeter of a cavity. In one embodiment, the alternating electric field is used to expose the cavity to sufficient energy for the ablation of the cavity. In one embodiment, two modes are used to expose different regions of the cavity to a different amount of energy so that the thermal effect is more uniform. In one embodiment, the electrodes have a relatively large surface area in order to prevent carbonization of the cavity, but are shaped to fit within a hole in the body. For example, the diameter of the sheath that houses the electrodes during penetration can be only 5.5 mm.
l '

类似技术:

公开号 | 公开日 | 专利标题

BR112012011021A2|2021-03-23|body cavity ablation device

US10456194B2|2019-10-29|System and method for endometrial ablation

BR112012011138B1|2020-11-03|system to perform a procedure on a patient's gynecological tract

US9050102B2|2015-06-09|System and method for endometrial ablation

US8939971B2|2015-01-27|System and method for endometrial ablation

US20100228239A1|2010-09-09|Ablation device with suction capability

US10932712B2|2021-03-02|Methods and systems for evaluating the integrity of a uterine cavity

BR112012001540B1|2020-03-10|SURGICAL APPLIANCE FOR THE REDUCTION OR REMOVAL OF SUSPENDED PARTICLES IN A LOCAL INTRACORPORAL ATMOSPHERE

BRPI0515208B1|2017-09-12|IMPLANT AND IMPLANT PLACEMENT INSTRUMENT

BRPI1106889B1|2020-05-26|Cobb electrosurgical lift instrument and electrosurgical system

ES2738646T3|2020-01-24|Real-time estimation of tissue perforation risk during minimally invasive medical procedure

BR102016016736A2|2017-03-14|ablation device for large area mucosa ablation

ES2856027T3|2021-09-27|Catheter and its manufacturing procedure

US10660697B2|2020-05-26|Hollow body cavity ablation apparatus

BR202019024962U2|2021-06-08|disposition introduced in bipolar electrode for resection

BR102019005894A2|2020-10-13|MULTIFUNCTIONAL INSTRUMENTAL FOR ENDONASAL SURGERY

CN216090748U|2022-03-22|Nasal septum plasma scalpel and plasma surgical equipment

US11246644B2|2022-02-15|Surface ablation using bipolar RF electrode

JP2003305055A|2003-10-28|Resectoscope apparatus

CN104068931A|2014-10-01|Renal denervation ablation catheter with rotatable flat electrode

同族专利:

公开号 | 公开日

CN102596082A|2012-07-18|

WO2011059487A3|2011-10-06|

US20150272670A1|2015-10-01|

EP2498708A2|2012-09-19|

US20110112524A1|2011-05-12|

EP2498708B1|2019-01-23|

CN102596082B|2015-02-18|

US9173702B2|2015-11-03|

US10758303B2|2020-09-01|

EP2498708A4|2013-04-24|

WO2011059487A2|2011-05-19|

引用文献:

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

US3924628A|1972-12-01|1975-12-09|William Droegemueller|Cyrogenic bladder for necrosing tissue cells|

US4016867A|1976-04-27|1977-04-12|The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare|Uterine caliper and depth gauge|

US4121572A|1977-02-07|1978-10-24|G.D. Searle & Co.|Uterine sound|

US4204548A|1977-12-17|1980-05-27|Kurz Karl H|Sound for insertion in the body for the determination of the internal measurements of hollow organs|

DE3330921C1|1983-08-27|1985-02-07|Karl-Heinz Dr.med. 4000 Düsseldorf Kurz|Device for determining the internal mass of hollow organs, especially the uterine cavity|

GB8607526D0|1986-03-26|1986-04-30|Artus R G C|Cooled component assembly|

US4873986A|1987-04-01|1989-10-17|Utah Medical Products|Disposable apparatus for monitoring intrauterine pressure and fetal heart rate|

US5613950A|1988-07-22|1997-03-25|Yoon; Inbae|Multifunctional manipulating instrument for various surgical procedures|

US4949718B1|1988-09-09|1998-11-10|Gynelab Products|Intrauterine cauterizing apparatus|

US4932421A|1989-01-23|1990-06-12|Steven Kaali|Electrified intrauterine device|

US5242390A|1991-05-03|1993-09-07|Goldrath Milton H|Endometrium coagulating surgical method for thermal destruction of the endometrium|

US5542928A|1991-05-17|1996-08-06|Innerdyne, Inc.|Method and device for thermal ablation having improved heat transfer|

US5383917A|1991-07-05|1995-01-24|Jawahar M. Desai|Device and method for multi-phase radio-frequency ablation|

US5520682A|1991-09-06|1996-05-28|Cryomedical Sciences, Inc.|Cryosurgical instrument with vent means and method using same|

US5562720A|1992-05-01|1996-10-08|Vesta Medical, Inc.|Bipolar/monopolar endometrial ablation device and method|

US5277201A|1992-05-01|1994-01-11|Vesta Medical, Inc.|Endometrial ablation apparatus and method|

US5324284A|1992-06-05|1994-06-28|Cardiac Pathways, Inc.|Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method|

US5275595A|1992-07-06|1994-01-04|Dobak Iii John D|Cryosurgical instrument|

WO1994002077A2|1992-07-15|1994-02-03|Angelase, Inc.|Ablation catheter system|

US5313943A|1992-09-25|1994-05-24|Ep Technologies, Inc.|Catheters and methods for performing cardiac diagnosis and treatment|

US5449380A|1993-09-17|1995-09-12|Origin Medsystems, Inc.|Apparatus and method for organ ablation|

US6530922B2|1993-12-15|2003-03-11|Sherwood Services Ag|Cluster ablation electrode system|

US5647868A|1994-02-02|1997-07-15|Chinn; Douglas Owen|Cryosurgical integrated control and monitoring system and method|

US5437629A|1994-04-14|1995-08-01|Bei Medical Systems|Fluid delivery system for hysteroscopic endometrial ablation|

US5575788A|1994-06-24|1996-11-19|Stuart D. Edwards|Thin layer ablation apparatus|

US5505730A|1994-06-24|1996-04-09|Stuart D. Edwards|Thin layer ablation apparatus|

US6009877A|1994-06-24|2000-01-04|Edwards; Stuart D.|Method for treating a sphincter|

US5540658A|1994-06-27|1996-07-30|Innerdyne, Inc.|Transcervical uterine access and sealing device|

US6142994A|1994-10-07|2000-11-07|Ep Technologies, Inc.|Surgical method and apparatus for positioning a diagnostic a therapeutic element within the body|

US5868740A|1995-03-24|1999-02-09|Board Of Regents-Univ Of Nebraska|Method for volumetric tissue ablation|

US5800493A|1995-04-26|1998-09-01|Gynecare, Inc.|Intrauterine ablation system|

US7276063B2|1998-08-11|2007-10-02|Arthrocare Corporation|Instrument for electrosurgical tissue treatment|

US5702438A|1995-06-08|1997-12-30|Avitall; Boaz|Expandable recording and ablation catheter system|

US6270495B1|1996-02-22|2001-08-07|Radiotherapeutics Corporation|Method and device for enhancing vessel occlusion|

US6033398A|1996-03-05|2000-03-07|Vnus Medical Technologies, Inc.|Method and apparatus for treating venous insufficiency using directionally applied energy|

US6033397A|1996-03-05|2000-03-07|Vnus Medical Technologies, Inc.|Method and apparatus for treating esophageal varices|

US5769880A|1996-04-12|1998-06-23|Novacept|Moisture transport system for contact electrocoagulation|

US6813520B2|1996-04-12|2004-11-02|Novacept|Method for ablating and/or coagulating tissue using moisture transport|

US7604633B2|1996-04-12|2009-10-20|Cytyc Corporation|Moisture transport system for contact electrocoagulation|

US5776129A|1996-06-12|1998-07-07|Ethicon Endo-Surgery, Inc.|Endometrial ablation apparatus and method|

US5891134A|1996-09-24|1999-04-06|Goble; Colin|System and method for applying thermal energy to tissue|

US5848969A|1996-10-28|1998-12-15|Ep Technologies, Inc.|Systems and methods for visualizing interior tissue regions using expandable imaging structures|

US5954714A|1996-11-20|1999-09-21|Gynecare, Inc.|Heated balloon having rotary fluid impeller|

US6048329A|1996-12-19|2000-04-11|Ep Technologies, Inc.|Catheter distal assembly with pull wires|

US5910104A|1996-12-26|1999-06-08|Cryogen, Inc.|Cryosurgical probe with disposable sheath|

US5916213A|1997-02-04|1999-06-29|Medtronic, Inc.|Systems and methods for tissue mapping and ablation|

US5868735A|1997-03-06|1999-02-09|Scimed Life Systems, Inc.|Cryoplasty device and method|

US5957920A|1997-08-28|1999-09-28|Isothermix, Inc.|Medical instruments and techniques for treatment of urinary incontinence|

EP1014873A4|1997-09-22|2003-07-09|Ethicon Inc|Cryosurgical system and method|

US6139538A|1997-10-06|2000-10-31|Iotek, Inc.|Iontophoretic agent delivery to the female reproductive tract|

US6161047A|1998-04-30|2000-12-12|Medtronic Inc.|Apparatus and method for expanding a stimulation lead body in situ|

US6514252B2|1998-05-01|2003-02-04|Perfect Surgical Techniques, Inc.|Bipolar surgical instruments having focused electrical fields|

US6522930B1|1998-05-06|2003-02-18|Atrionix, Inc.|Irrigated ablation device assembly|

US6508815B1|1998-05-08|2003-01-21|Novacept|Radio-frequency generator for powering an ablation device|

US6221039B1|1998-10-26|2001-04-24|Scimed Life Systems, Inc.|Multi-function surgical instrument|

US6190382B1|1998-12-14|2001-02-20|Medwaves, Inc.|Radio-frequency based catheter system for ablation of body tissues|

US6547784B1|2000-06-23|2003-04-15|Ethicon, Inc.|System and method for placement of a surgical instrument in a body cavity|

US6620161B2|2001-01-24|2003-09-16|Ethicon, Inc.|Electrosurgical instrument with an operational sequencing element|

US7422586B2|2001-02-28|2008-09-09|Angiodynamics, Inc.|Tissue surface treatment apparatus and method|

US6960203B2|2002-06-26|2005-11-01|Ethicon, Inc.|Thermal ablation with deployable cage|

US6929642B2|2002-06-28|2005-08-16|Ethicon, Inc.|RF device for treating the uterus|

US20040002702A1|2002-06-28|2004-01-01|Ethicon, Inc.|RF device for treating the uterus|

US7101367B2|2002-09-30|2006-09-05|Ethicon, Inc.|Deployable cryosurgical catheter|

US7115124B1|2003-11-12|2006-10-03|Jia Hua Xiao|Device and method for tissue ablation using bipolar radio-frequency current|

US7481808B2|2004-06-30|2009-01-27|Ethicon, Inc.|Flexible electrode device and surgical apparatus equipped with same|

US20060089636A1|2004-10-27|2006-04-27|Christopherson Mark A|Ultrasound visualization for transurethral needle ablation|

JP2006288755A|2005-04-11|2006-10-26|Olympus Medical Systems Corp|Medical treatment device|

AU2006268238A1|2005-07-11|2007-01-18|Medtronic Ablation Frontiers Llc|Low power tissue ablation system|

US8657814B2|2005-08-22|2014-02-25|Medtronic Ablation Frontiers Llc|User interface for tissue ablation system|

US9333026B2|2005-11-18|2016-05-10|Boston Scientific Scimed, Inc.|Radio frequency lasso|

US20090062795A1|2007-08-31|2009-03-05|Ethicon Endo-Surgery, Inc.|Electrical ablation surgical instruments|

WO2010053700A1|2008-11-10|2010-05-14|Microcube, Llc|Methods and devices for applying energy to bodily tissues|

WO2011059487A2|2009-11-10|2011-05-19|Cardea MedSystems, Inc.|Hollow body cavity ablation apparatus|

US10660697B2|2009-11-10|2020-05-26|Cardea Medsystems Co., Ltd.|Hollow body cavity ablation apparatus|US8372068B2|2008-10-21|2013-02-12|Hermes Innovations, LLC|Tissue ablation systems|

US9662163B2|2008-10-21|2017-05-30|Hermes Innovations Llc|Endometrial ablation devices and systems|

US8540708B2|2008-10-21|2013-09-24|Hermes Innovations Llc|Endometrial ablation method|

US8500732B2|2008-10-21|2013-08-06|Hermes Innovations Llc|Endometrial ablation devices and systems|

US8197477B2|2008-10-21|2012-06-12|Hermes Innovations Llc|Tissue ablation methods|

US8197476B2|2008-10-21|2012-06-12|Hermes Innovations Llc|Tissue ablation systems|

US10660697B2|2009-11-10|2020-05-26|Cardea MedsystemsCo., Ltd.|Hollow body cavity ablation apparatus|

WO2011059487A2|2009-11-10|2011-05-19|Cardea MedSystems, Inc.|Hollow body cavity ablation apparatus|

US8715278B2|2009-11-11|2014-05-06|Minerva Surgical, Inc.|System for endometrial ablation utilizing radio frequency|

US8821486B2|2009-11-13|2014-09-02|Hermes Innovations, LLC|Tissue ablation systems and methods|

US9289257B2|2009-11-13|2016-03-22|Minerva Surgical, Inc.|Methods and systems for endometrial ablation utilizing radio frequency|

US8529562B2|2009-11-13|2013-09-10|Minerva Surgical, Inc|Systems and methods for endometrial ablation|

CN102223424A|2010-04-16|2011-10-19|鸿富锦精密工业（深圳）有限公司|Mobile phone|

US8956348B2|2010-07-21|2015-02-17|Minerva Surgical, Inc.|Methods and systems for endometrial ablation|

US9510897B2|2010-11-05|2016-12-06|Hermes Innovations Llc|RF-electrode surface and method of fabrication|

US9028487B2|2011-06-21|2015-05-12|Cook Medical Technologies Llc|Expandable probe|

EP2811921B1|2012-02-09|2020-01-08|Boston Scientific Scimed, Inc.|Cutting tool with circulating wire|

US9901394B2|2013-04-04|2018-02-27|Hermes Innovations Llc|Medical ablation system and method of making|

US9649125B2|2013-10-15|2017-05-16|Hermes Innovations Llc|Laparoscopic device|

US20150173828A1|2013-12-23|2015-06-25|Boaz Avitall|Small loop ablation catheter|

JP6362895B2|2014-03-24|2018-07-25|テルモ株式会社|Therapy device|

US10492856B2|2015-01-26|2019-12-03|Hermes Innovations Llc|Surgical fluid management system and method of use|

CN104739504B|2015-02-28|2017-03-22|上海凯利泰医疗科技股份有限公司|Radiofrequency ablation device for spinal neoplasms operation|

WO2016175980A1|2015-04-29|2016-11-03|Csaba Truckai|Medical ablation device and method of use|

WO2017095689A1|2015-12-02|2017-06-08|St. Jude Medical, Cardiology Division, Inc.|Radiofrequency ablation device|

US10603101B2|2016-03-26|2020-03-31|Paul Joseph Weber|Apparatus, systems and methods for minimally invasive dissection of tissues|

WO2017185097A1|2016-04-22|2017-10-26|RELIGN Corporation|Arthroscopic devices and methods|

JP2020511205A|2017-03-22|2020-04-16|マグネトスロムベクトミィソリューションズリミテッド|Thrombectomy using both electrostatic force and suction force|

US10682496B2|2017-11-16|2020-06-16|Biosense WebsterLtd.|Catheter handle|

US11149318B2|2018-01-29|2021-10-19|Graphene-Dx, Inc.|Methods and devices for detection of pathogens|

CN111772783A|2020-08-21|2020-10-16|白龙腾|Ablation system with bendable electrodes|

法律状态:
2021-03-30| B15I| Others concerning applications: loss of priority|Free format text: PERDA DA PRIORIDADE US 61/259,973 DE 10.11.2009 POIS A EXIGENCIA PUBLICADA NA RPI 2608 DE 29/12/2020 RELATIVA A CESSAO DESTA PRIORIDADE NAO FOI DEVIDAMENTE RESPONDIDA. |

2021-04-06| B25A| Requested transfer of rights approved|Owner name: CARDEA MEDSYSTEMS (TIANJIN) CO., LTD. (CN) |

2021-04-13| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|

2021-04-13| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|

2021-08-03| B06A| Patent application procedure suspended [chapter 6.1 patent gazette]|

2022-01-25| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|

优先权:

申请号 | 申请日 | 专利标题

US25997309P| true| 2009-11-10|2009-11-10|

PCT/US2010/002944|WO2011059487A2|2009-11-10|2010-11-10|Hollow body cavity ablation apparatus|

[返回顶部]